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Int. J. Nanobiotechnol. Pharm.

Articles of  Int. J. Nanobiotechnol. Pharm. are distributed worldwide by Mail Services and with help of annual subscription or purchasing single copy. THERE

Microbiology, biotechnology and biochemistry

The using of microbial enzymes in the area of chemical, biotechnological and pharmacological industries has been carried out for a long time. HERE

Separating molecules, but uniting people

Problems of development of chemistry as a science are reflected in the new monographs replenished funds Information and Library Center of Tyumen State University . March 21, 1903 Russian scientist, Professor Mikhail Tsvet (1872-1919) at the meeting of the Warsaw Society of Naturalists first introduced in the scientific speech the term "chromatography" — a dynamic method for the separation and analysis of mixtures of substances.
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Isolation of the terpestacin from the endophytic fungus Drechslera ravenelii

Studies about biprospection in endophytic fungi isolated from Smalanthus sonchifolius, the fermentation in solid medium rice-oat by 720 hours of the fungus Drechslera ravenelii (SS33) led to the isolation of sesterpene terpestacin. The molecule terpestacin has attracted the scientific community attention due to inhibitory activity in the syncytium formation caused by the HIV virus and also by presenting unusual chemical structure. After fermentation in the rice-oat medium, the hydroalcoholic extract was submitted to the liquid-liquid partition with n-hexane, dichloromethane, ethyl acetate and butanol. The dichlorometanic fraction was subjected to chromatographic processes to obtain 19.0 mg of terpestacin. The structure of this compound was were elucidated by detailed spectroscopic analyses. This study reported the isolation of terpestacin from the endophytic fungus Drechslera ravenelii for the first time.
Eliane O. Silva, Willian J. Andrioli, Adriana A. Lopes, Monica T. Pupo, Jairo K. Bastos. Isolation of the terpestacin from the endophytic fungus Drechslera ravenelii. International Journal of Nanobiotechnology and Pharmacy. 2013. N2. p.2-7.
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